Professor

Phone: 027-87792271

Email: lisu@hust.edu.cn

Academic Areas: Biochemistry anad Molecular Biology

Research Interests: Cellular and Immunol Biology of Cancer

Academic Degrees

Ph.D. in Pathology, 2003, Kyoto University, Japan;

MS in Biology, 1991, Wuhan University, Wuhan, China;

BA in Biology, 1991, Wuhan University, Wuhan, China.

Professional Experience

Professor (2007-present): College of Life Science and Technology, Huazhong University of Science and Technology

Research Scientist (2005-2007): Stanford Research Institute, California, USA

Research Scientist (2003-2005): Japan Society for the Promotion of Science (JSPS) and Research Center For Allergy and Immunology, RIKEN, Japan

Lecture (1991-2004): School of Life Science, Wuhan University, China

 

Selected Publications

1. Zhang Z, Zhang W, Huang S, Sun Q, Wang Y, Hu Y, Sun N, Zhang Y, Jiang Z, Minato N, Pin JP, Su L*, Liu J. GABAB receptor promotes its own surface expression by recruiting a Rap1-dependent signaling cascade. J Cell Sci. 2015; 128(12):2302-13.

2. Zhu Q, Zhu P, Zhang Y , Li J, Ma X, Li L, Wang Q, Xue X, Luo L, Li L, Ring HZ, Ring BZ, Li Su*. Analysis of Social and Genetic Factors Influencing Heterosexual Transmission of HIV within Serodiscordant Couples in the Henan Cohort. PLoS One. 2015 Jun 11;10(6):e0129979.

3. Feng AP, Zhang Q, Li M, Jiang XN, Zhang ZY, Zhu P, Wang MW, Wei SZ, Su L*. High SIPA-1 expression in proximal tubules of human kidneys under pathological conditions. J Huazhong Univ Sci Technolog Med Sci. 2015;35(1):64-70. 

4. Zhang Y, Gong Y, Hu D, Zhu P, Wang N, Zhang Q, Wang M, Aldeewan A, Xia H, Qu X, Ring BZ, Minato N, Su L*. Nuclear SIPA1 activates integrin β1 promoter and promotes invasion of breast cancer cells. Oncogene, 2014; 34(11):1451-62.

5. Ali B. Aldeewan, Zhang Y and Su L*. Bacillus thuringiensis Parasporins Functions on Cancer Cells. Int. J. Pure App. Biosci. 2014, 2 (4): 67-74.

6. Ali B. Aldeewan, Zhang Y, Meng Y, Peng D, Yu Z, Sun M, Ring BZ and Su L*. A Novel Bacillus thuringiensis Crystal Protein Cry51Aa1with Preferentially Anti-cancer Activity. Journal of Pure and Applied Microbiology, 2014, 8(4): 2637-2644

7. Yang Y, Luo L, Xu J, Zhu P, Xue W, Wang J, Li W, Wang M, Cheng K, Liu S, Tang Z, Ring BZ, Su L*. Novel EDA p.Ile260Ser mutation linked to non-syndromic hypodontia. Journal of Dental Research, 2013; 92(6):500-506.

8. Zhu P, Zhu Q, Zhang Y, Ma X, Li Z, Li J, Chen J, Luo L, Ring HZ, Ring BZ, Su L*. ABCB1 variation and treatment response in AIDS patients: initial results of the Henan cohort, PLoS ONE, 2013; 8(1): e55197.

9. Yan J, Jia H, Ma Z, Ye H, Zhou M, Su L, Liu J, Guo AY. The evolutionary analysis reveals domain fusion of proteins with Frizzled-like CRD domain. Gene. 2014; 533(1):229-39.

10. Jiang X, Su L, Zhang Q, He C, Zhang Z, Yi P, Liu J. GABAB receptor complex as a potential target for tumor therapy. J Histochem Cytochem. 2012, 60(4):269-79. 

11. Li X, Hu Z, Qu X, Zhu J, Li L, Ring BZ, Su L*,Putative EPHX1 Enzyme Activity Is Related with Risk of Lung and Upper Aerodigestive Tract Cancers: A ComprehensiveMeta-Analysis. PLoS ONE, 6(3):e14749, 2011

12. Hu Z, Li X, Qu X, He Y, Ring BZ, Song E, Li Su*. Intron 3 16bp duplication polymorphism of TP53 contributes to cancer susceptibility: a meta-analysis. Carcinogenesis. 2010, 31(4):643-7

13. Hu Z, Li X, Yuan R, Ring BZ, Li Su*. Three common TP53 polymorphisms in susceptibility to breast cancer, evidence from meta analysis, Breast Cancer Research and Treatment, 2010,120(3):705-14 

14. Daisuke Ishida*, Li Su*, Yoriko Shinozuka, Yohei Kawai, Masashi Taniwaki, Yoko Hamazaki, Masakazu Hattori, and Nagahiro Minato.  Rap1 Signal Controls B Cell Receptor Repertoire and Generation of self-reactive B1a cells. Immunity, 2006, 24:417-427

15. Li.Su, Masaki Moriyama, Norihito Murata, Masashi Harazaki, Kozo Kaibuchi, and Nagahiro Minato; AF-6 and SPA-1 Form a Molecular Complex and Negatively Regulate Integrin-dependent Cell adhesion via Efficient Rap1 Inactivation, The Journal of Biological Chemistry, 2003, 278(17):15232-15238

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