Associate professor

Phone: (027)87792073-208

Email: tuzhiming@hust.edu.cn; tuzhiming9@sina.com

Academic Areas: Molecular Biology

Research Interests: Modernization of TCM and its molecular mechanism; Isolation and identification of genes and their promoters;Gene diagnosis and gene therapy.

Academic Degrees

PhD in Biochemistry & Molecular Biology, 2007, Huazhong University of Science and Technology, Wuhan, China;

PhD candidate in molecular Biology,1999, School of Biological Sciences, The University of Sydney, Sydney, Australia.

Master’s degree in Molecular Biology, 1990, Wuhan Institute of Virology, Academia Sinica, Wuhan, China.

Postgraduate diploma in Genetics ,  1987,  Zhejiang University, Hangzhou, China.

BA in Biology, 1985, Hubei University, Wuhan, China.

Professional Experience

Associate Professor (2001-present), School of Life Science, Huazhong University of Science and Technology, Wuhan, China.

Visiting Scholar (2005), Australian Endeavour Cheung Kong Awards, Medical school of Flinders University, Adelaide, Australia.

Associate Professor (1998-2001), Medical School of Wuhan University, Wuhan, China.

Lecturer (1988-1997), Medical School of Wuhan University (Hubei Medical University), Wuhan, China.

Selected Publications

1. Tu Zhiming,Zhang Jiangzhou, Chen Ling,Qin Chuan, Yang Guangxiao,  He Guangyuan. Isolatin of a pollen-specific promoter in tritordeum,Engineering Science, 2011,9(1):72-75

2. Tu Zhiming,Zhang Jiangzhou, Yang Guangxiao,  He Guangyuan. Characterization of alkaline phosphatase labelled UidA(GUS) probe and its application in testing of transgenic plant, Molecular biology  report, 2011;38(2):1413-7.

3. Tu Zhiming, Li-Hua Ke,Guangyuan He. The Application of Alkaline Phosphatase Labeled HBV Probe in Serum Detection,Virus Genes, 2004,28(2):153 –158. (SCI)

4. Jiangzhou Zhang, Zhiming Tu. Neuroprotection by Ginsenoside Rg1 against beta-amyloid-induced apoptosis is mediated by PI-3K/Akt/GSK-3 beta signaling pathway.Journal of the American Geriatrics Society(JAGS),2009,57(SUPPL1),s56(SCIImpact factor=3.539)

5. Ling Chen,Zhiming Tu,Javeed Hussain,Ling Cong,Yinjun Yan,Lian Jin,Guangxiao Yang,Guangyuan He.Isolation and heterologous transformation analysis of a pollen-specific promoter from wheat (Triticum aestivum L.).  Mol Biol Rep, 2010,37:737–744

6. Jiang Z, Xu J, Long M, Tu Z, Yang G, He G. 2, 3, 5, 4'-tetrahydroxystilbene-2-O-beta-D-glucoside (THSG) induces melanogenesis in B16 cells by MAP kinase activation and tyrosinase upregulation. Life Sci. 2009,85(9-10):345-50

7. Tu Zhiming, Fang Huazhou, Du Hong. Application of research of RNAi technique in medicine. CHINESE JOURNAL OF BIRTH HEALTH & HEREDITY,2007,15(4):1-3.

8. Jian-Ping Gan, Zhong-Hua Wu, Zhi-Ming Tu, Jian Zheng. The Comparison of Twinning Rates Between Urban and Rural Areas in China.Twin Research and Human Genetics, 2007,10(4):633-637(SCI)

9. TU Zhi-ming,CHEN Lin,YANG Guang-xiao,HE Guang-yuan.  Application of enzyme-labeled probe in transgenic plant. HEREDITAS(Beijing),2007, 29 (12): 1533-1537

10. TU Zhi-ming,CHEN Lin,YANG Guang-xiao,HE Guang-yuan. Tagging and Isolation   of the Anther-specific Promoter in hexaploid tritordeum, Journal of Wuhan Botanical Research, 2007,25(4): 321-325

11. Tu Zhiming, Chen Minjie, He Guangyuan, Chang Junli.An improved system for competent cell preparation and plasmid transformation, Journal of Huazhong University of Science and Technology (Nature Science), 2006,34(4):112-115.

12. Tu Z.M, G.Y. He, Chris Gillies, J.T. Zhao, The structure, functions and evolution of Su (Ste) repeats on the Y chromosome of Drosophila melanogaster, Journal of Entomology, 2005,2(1): 46-51

13. Tu Z.M, G.Y.He,etc. An improved system for competent cell preparation and high efficiency plasmid transformation using different Escherichia coli strains. Electronic Journal of Biotechnology [online],April 15th, 2005, Available from: http://www.ejbiotechnology.info/content/vol2/issue3/full/3/index.html. ISSN 0717-3458. SCI

14. Tu Z.M, G.Y. HE, etc. Clone of the tissue specific promoters in Durum wheat, Poster presentation on ComBio2005 (Combined Conference of Australian Society for Biochemistry and Molecular Biology, Australia and New Zealand Society for Cell & Developmental Biology, and Australian Society of Plant Scientists), Sept. 2005, Adelaide, Australia

15. Tu Zhiming, Hong Huili. The early development study on the chromosomal abnormal embryo. Chinese Journal Of Birth Health & Heredity,1999,7(2):58.

16. Tu Zhiming, He guangyuan, yulongjiang. Teach Zoology by English and multimedia to meet the challenge of globlization,Modern China Education Forum,Beijing, 2003, p.329-335

17. Tu Zhiming. Teach Biology in English for Globlization. China Education Reform (Hongkong), 2006, 69(8): 13-14.

Books

  1. Liu yanping,Tu zhiming,etc, 《Experiment protocol for Cell Biology》, 2015,Peoples’s Medical publishing House;
  2. Zuo Ji, Liu yanping,Tu zhiming,etc, 《Cell Biology》, 2015,Peoples’s Medical publishing House;
  3. Su Li, Tu zhiming,etc, 《 Practical Guidance for Cell Biology Experiments》, 2015,HUST publishing House;
  4. Xu Jin, Tu zhiming,etc,《Cell Biology Learning Guidance and Questions》, 2015,Peoples’s Medical publishing House;
  5. Tu zhiming, 《An outline of Zoology》, Huazhong University of Science & Technology, 2001
  6. Tu Zhiming, Biology Glossary, Huazhong University of Science and Technology,  2006

Courses Taught

ZoologyGeneral Biology Introduction to Life Science, Cell Biology for undergraduates/ international students;

Advanced medical biology for graduates;

Project

1. Making a Y-gene diagnosis kit (1998, Hubei Medical University);

2. Making a HBV probe and applied in serum test(1988-1990, Wuhan Institute of Virology, Academia Sinica);

3. Research on the chromosome aberration and gene mutation in lung cancer(1999, NSFS,No.39870305,A,C03030203);

4. Genetic improvement of wheat characters and its application(J99-B-009,“863”,“973”,2004);

5. Molecular mechanism of Belamcanda chinensis from Dabie mountain(2005, “973” 2005CCA1900);

6. Guangdong province and China Education Ministry joint production-education-research funding, Recognizing system based on human face characters(No:2009B090300198,2009-2010);

7. National University Basic Research Funding of (20090109170014) Isolation a pollen-specific promoter in tritordeum(2008-2011);

8. PhD dissertation Foundation of Huazhong University of Science & Technology. (2008-2011);

9. TRPM8 Ca 2+ channel: a new prostate cancer marker . Flinder’s Medical Center, Adelaide, Australia(2005);

 

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