Professor

Phone: 027-87793102

Email: cong.ma@hust.edu.cn

Academic Areas: Molecular Biophysics

Research Interests: Neurotransmitter release and membrane fusion

Academic Degrees

09/2007 - 08/2011    UT Southwestern Medical Center at Dallas, USA   (Biophysics), Postdoctoral research    

09/2004 - 07/2007   Huazhong University of Science & Technology, Wuhan, China (Biophysics), Doctor

09/2000 - 06/2003   Huazhong University of Science & Technology, Wuhan, China (Environmental science), Master    

09/1996 -  06/2000   South-Center University For Nationalities, Wuhan, China (Biochemistry), Bachelor

Professional Experience

09/2011 - Present       School of Life Science & Technology, Huazhong University of Science & Technology, Wuhan, China, Professor       

09/2003 - 04/2004   University of Munich, Germany       (Environmental science), Visiting Scholar   

Selected Publications

1: Wang S#, Li Y#, Ma C*. Synaptotagmin-1 C2B domain interacts simultaneously with SNAREs and membranes to promote membrane fusion. Elife. e14211. doi: 10.7554. (2016)

2: Yang X#, Wang S#, Sheng Y#, Zhang M, Zou W, Wu L, Kang L, Rizo J, Zhang R, Xu T*, Ma C*. Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming. Nat Struct Mol Biol. 22(7):547-54. (2015)

3: Ma C#*, Su L#, Seven AB, Xu Y, Rizo J*. Reconstitution of the Vital Functions of Munc18 and Munc13 in Neurotransmitter Release. Science. 339(6118):421-5. (2013)

4: Li W#, Ma C#, Guan R, Xu Y, Tomchick D.R* and Rizo J*. The Crystal Structure of a Munc13 C -terminal Module Exhibits a Remarkable Similarity to Vesicle Tethering Factors. Sturcture. 19(10):1443-55. (2011)

5: Ma C#, Li W#, XU Y, Rizo J*. Munc13 mediates the transition from the closed Syntaxin/Munc18 complex to the SNARE complex. Nat Struct Mol Biol. 18(5):542-9. (2011)

6: Xue M#, Ma C#, Craig TK, Rosenmund C*, Rizo J*. The Janus-faced Nature of the C(2)B Domain is Fundamental for Synaptotagmin-1 Function. Nat Struct Mol Biol. 15(11):1160-8. (2008)

 

Awards and Honors

1: Cheung Kong Young Scholar (the Ministry of Education, 2016), China

2: National Top-Notch Young Talent (the National High-level Personnel of Special Support Program, 2015), China

3: Outstanding Young Scholar (the National Natural Science Foundation, 2013), China

4: New Century Excellent Talent (the Ministry of Education, 2013), China

 

Courses Taught

Biophysics (0700991)

Advanced Biophysics (170.551)

Advanced Neurobiology (170.552)

Project

1: “Mechanism Study of Munc13-1 in Neurotransmitter Release”, 31370819, National Science Foundation of China, 01/2014-12/2017.

2: “Neurotransmitter Release and Membrane Fusion”, 31322034, National Science Foundation of China, 01/2014-12/2016.

3: “Protein Machinery for Axon Growth and Synaptic Transmission”, 2014CB910203, National Key Basic Research Program of China, 01/2014-12/2018.

4: “Develop a new single-molecule biophysical technique to study dynamic conformations and functions of synaptic transmembrane proteins on neural cells”, 2015CB910800, (Group member), National Key Basic Research Program of China (Young Scientist Program), 01/2015-8/2019.

 

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