Professor
Phone: 00
Email: hexj@hust.edu.cn
Academic Areas: Biophysics
Research Interests: During development of the nervous system, axons are guided to their proper targets by sensing a variety of extracellular cues in the local environment. The signal finally selectively alters the stability of the actin cytoskeleton and microtubules
Academic Degrees
Ph.D. in Biochemistry and molecular biology
Professional Experience
Sep2005~Oct 2008 Research Assistant
Institute of Biophysics, CAS, Beijing
Sep2008 ~Feb 2014 Postdoctoral Researcher & Assistant Instructor
UT Southwestern Medical Center, US
Feb 2014~PRESENT Professor； Principal Investigator
School of Life Science and Technology,
Huazhong University of Science and Technology, Wuhan,China
Selected Publications
- He S, Zhao J, Song S, He X, Minassian A, Zhou Y, Zhang J, Brulois K, Wang Y, Cabo J, Zandi E, Liang C, Jung J, Zhang X, and Feng P* Viral Pseudo Enzymes Activate RIG-I via Deamidation to Evade Cytokine Production. Mol Cell. 2015 ;58(1): 134–146.
- Xu H, He X, Zheng H, Huang LJ, Hou F, Yu Z, Cruz MJ, Borkowski B, Zhang X*, Chen ZJ*, Jiang QX* Structural basis for the prion-like MAVS filaments in antiviral innate immunity, Elife, 3:e01489, 2014
- He X, Kuo YC, Rosche TJ, Zhang X* Structural basis for autoinhibition of the guanine nucleotide exchange factor FARP2, Structure, 21(3):355-64, 2013
- Yuan P, Bartlam M, Lou Z, Chen S, Zhou J, He X, Lv Z, Ge R, Li X, Deng T, Fodor E, Rao Z, Liu Y. Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site. Nature. 2009 Apr 16;458(7240):909-13.
- He X, Zhou J, Bartlam M, Zhang R, Ma J, Lou Z, Li X, Li J, Joachimiak A, Zeng Z, Ge R, Rao Z, Liu Y. Crystal structure of PAc: PB1N complex from bird flu H5N1. Nature. 2008 Aug 28;454(7208):1123-6.
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