Li Hui

Academic Degrees

M.D. in Pathogenic biology, 2005, Wuhan University

M.S in Pathogenic biology, 2002, Wuhan University

B.S. in Clinical medicine, 1998, Wuhan University

Professional Experience

Associate Professor (2009-present) Department of Genetics and Developmental biology in Huazhong University of Science & Technology;

Lecturer (2008-2009) Department of Genetics and Developmental biology in Huazhong University of Science & Technology

Post-Docotor (2005-2008) Department of Genetics and Developmental biology in Huazhong University of Science & Technology

Selected Publications

1. Chen, JX ; Liu, F ; Li H ; Archacld, S; Gao, M ; Liu, Y ; Liao, SJ ; Huang, M; Wang, JX ; Yu, SS; Li, C ; Tang, ZH ; Liu, MG. pVHL interacts with Ceramide kinase like (CERKL) protein and ubiquitinates it for oxygen dependent proteasomal degradation. CELLULAR SIGNALLING. 2015;27: 2314-2323.

2. Zeng, H ; Chen, YL ; You, WT ; Huang, XQ ; Zhou, CY ; Li, H miR-491-5p functions as a tumor suppressor by targeting JMJD2B in ER alpha-positive breast cancer. FEBS LETTERS. 2015; 589: 812-821.

3. Wang N; Zhou Y ; Zheng LJ ; Li H. MiR-31 is an independent prognostic factor and functions as an oncomir in cervical cancer via targeting ARID1A. GYNECOLOGIC ONCOLOGY. 2014; 134:129-137.

4. Wang N, Zhan T, Ke T, Huang X, Ke D, Wang Q, Li H. Increased expression of RRM2 by human papillomavirus E7 oncoprotein promotes angiogenesis in cervical cancer. Br J Cancer. 2014;110(4):1034-44.

5. Li H, Zhan T, Li C, Liu M, Wang QK. Repression of MHC class I transcription by HPV16E7 through interaction with a putative RXRbeta motif and NF-kappaB cytoplasmic sequestration. Biochem Biophys Res Commun. 2009 Oct 16;388(2):383-8.

6. Li H, Chang li, Qiulun Lu, Su Ting, Tie Ke, Cheng W Li, Mingxiong Yuan, Jingyu Liu, Xiang Ren, Zhihong Zhang, Shaoqiong Zeng, Qing K. Wang, Mugen Liu. Cataract mutation P20S of aB-crystallin impairs chaperone activity of aA-crystallin and induces apoptosis of human lens epithelial cells. BBA-MOL BASIS DIS 2008 May;1782(5):303-9.

7. Li H, Ou X, and Xiong JH. Modified HPV16 E7/HSP70 DNA vaccine with high safety and enhanced cellular immunity represses murine lung metastatic tumors with downregulated expression of MHC class I molecules.Gynecol Oncol. 2007;104:564-71

8. Li H, Ou X, and Xiong JH, et al. HPV16E7 mediates HDAC chromatin repression and downregulation of MHC class I genes in HPV16 tumorigenic cells through interaction with an MHC class I promoter.Biochemical and Biophysical Research Communications.2006;349:1315-21

Courses Taught

170.535：Foundations of molecular medicine (MS course)