Professor

Phone: 86-27-87793080

Email: qgxie@mail.hust.edu.cn

Academic Areas: Physics; Biomedical Engineering; Medical Electronics

Research Interests: My research interests are focused on digital PET system development and application extension.

Academic Degrees

Ph.D

Professional Experience

12/18/2013 – present

Distinguished Professor, Biomedical Engineering Department, Huazhong University of Science and Technology, Wuhan, Hubei, China

05/10/2008 – present

Professor, Biomedical Engineering Department, Huazhong University of Science and Technology, Wuhan, Hubei, China (Date of Appointment: 11/16/2007)

Adjunct Investigator, Wuhan National Laboratory for Optoelectronics, Wuhan, China

Director of PET Instrumentation Development and Multi-Modality Medical Imaging Laboratory

Vice Director of Hubei Provincial Key Laboratory of Bio-informatics and Molecular Imaging

Director of Molecular Imaging Engineering Division of Hubei Provincial Key Laboratory of Molecular Imaging (HUST Union Hospital), Wuhan, Hubei, China

Unit Coordinator for elective course in PET Fundamentals

2010-present

Unit Coordinator for graduate student course in Biomedical Digital Signal Processing (2008-2010)

Unit Coordinator for core courses in Digital Signal Processing

2007-2010

Unit Coordinator for elective course in Hospital Information System

2007-2009

03/31/2006 – 05/09/2008

Post-doctoral Scholar/Assistant Professor (Research Track), Department of Radiology, The University of Chicago, Chicago, Illinois, USA

11/15/2005 – 03/30/2006

Associate Professor, Department of Biomedical Engineering, Huazhong University of Science and Technology, Wuhan, Hubei, China (Date of Appointment: 06/01/2003)

Adjunct investigator, Wuhan National Laboratory for Optoelectronics, Wuhan, China

Director of PET Instrumentation Development and Multi-Modality Medical Imaging Laboratory

Vice Director of Hubei Provincial Key Laboratory of Bio-informatics and Molecular Imaging

09/29/2004 – 11/14/2005

Associate Professor, Department of Control Science and Engineering, Huazhong University of Science and Technology, Wuhan, Hubei, China (Date of Appointment: 06/01/2003)

Director of PET Laboratory

Unit Coordinator for core courses in Microcomputer System Architecture and Interfacing, and Computer Networks

Unit Coordinator for elective course in Java Programming

09/29/2002 - 09/28/2004

Post-doctoral Fellow, Medical Engineering Research Division, National Health Research Institutes, Taipei, Taiwan

01/02/2001 - 09/28/2002

Lecturer (Assistant Professor), Department of Control Science and Engineering, Huazhong University of Science and Technology, Wuhan, Hubei, China (Date of Appointmnet: 05/01/2000)

Member, Inverted Pendulum Experiments Committee (10/2001 – 09/2002)

Selected Publications

[1] BaichengLi, Yue Wang, Daoming Xi, Chenhui Li, Chen Zeng, Ruiheng Wang, Kun Liang, Ru Yang, Qingguo Xie, Dejun Han. "Feasibility Study on Silicon Photomultiplier with Epitaxial Quenching Resistors as the Readout for PET Detectors." IEEE Transactionson Nuclear Science 63, no. 11 (2016): 17-21.

[2] YanzhaoLi, Peng Xiao, Xiaohua Zhu, Qingguo Xie. "Multi-Resolution Multi-Sensitivity Design for Parallel-Hole SPECT Collimators." Physics in Medicine and Biology 61, no. 14 (2016): 5390-405.

[3] Mohamed A. A. Ahmed, Peng Xiao, Qingguo Xie. "New Approach for Simultaneous Respiratory and Cardiac Motion Correction in Cardiac PET (NAMC-CPET)." Physics in Medicine and Biology 60, no. 19 (2015): 7779-804.

[4] XiaoqingCao, Qingguo Xie, Peng Xiao. "A Regularized Relaxed Ordered Subset List-Mode Reconstruction Algorithm and its Preliminary Application to Undersampling PET Imaging." Physics in Medicine and Biology 60, no. 1 (2015): 49-66.

[5] Zhenzhou Deng, Qingguo Xie. "Quadratic Programming Time Pickoff Method for Multivoltage Threshold Digitizer in PET." IEEE Transactionson Nuclear Science 62, no. 31 (2015): 805-13.

[6] N. D’Ascenzo, P.S. Marrocchesi, C.S. Moon, F. Morsani, L. Ratti, V. Saveliev, A. Savoy Navarro and Qingguo Xie, Silicon avalanche pixel sensor for high precision tracking, Journal of Instrumentation, 2014 (accepted)

[7] Jinxia Guo, Lixin Lang, Shuo Hu, Ning Guo, Lei Zhu, Zhongchan Sun, Ying Ma, Dale O. Kiesewetter, Gang Niu, Qingguo Xie and Xiaoyuan Chen, Comparison of three dimeric 18F-AIF-NOTA-RGD tracers, Molecular Imaging and Biology, vol. 16, pp. 274-283, 2014

[8] Jinxia Guo, Ning Guo, Lixin Lang, Dale O. Kiesewetter, Qingguo Xie, Quanzheng Li, Henry S. Eden, Gang Niu and Xiaoyuan Chen, 18F-Alfatide II and 18F-FDG dual-tracer dynamic PET for parametric, early prediction of tumor response to therapy, Journal of Nuclear Medicine, vol. 55, pp. 154-160, 2014

[9] Qingguo Xie, Lu Wan, Xiaoqing Cao and Peng Xiao, Conceptual design and simulation study of an ROI-focused panel-PET scanner, PLoS One, vol. 8, no. 8, pp. e72109, 2013

[10] Peng Xiao, Xiaoqing Cao, Lu Wan and Qingguo Xie, TOF capability evaluation on a panel PET for human body imaging, Journal of Instrumentation, vol. 8, no. 4, pp. P04001, 2013

[11] Weixing Wan, Ning Guo, Donghui Pan, Chunjing Yu, Yuan Weng, Shineng Luo, Hong Ding, Yuping Xu, Lizhen Wang, Lixin Lang, Qingguo Xie, Min Yang and Xiaoyuan Chen, First experience of 18F-Alfatide in lung cancer patients using a new-lyophilized kit for rapid radiofluorination, Journal of Nuclear and Medicine, vol. 54 , pp. 691-698, 2013

[12] Zhenzhou Deng, Qingguo Xie, Zhiwen Duan and Peng Xiao, Scintillation event energy measurement via a pulse model based iterative deconvolution method, Physics in Medicine and Biology, vol. 58, pp. 7815-7827, 2013

[13] Luyao Wang, Jun Zhu, Xiao Liang, Ming Niu, Xiaoke Wu, Chien-Min Kao, Heejong Kim, Qingguo Xie. "Performance Evaluation of the Trans-PET (R) BioCaliburn (R) LH System: A Large FOV Small-Animal PET System." Physics in Medicine and Biology 60, no. 1 (2015): 137-50.

[14] Chunhui Zhang, Xueli Chen, Shouping Zhu, Lu Wan, Qingguo Xie, Jimin Liang. "Performance Evaluation of a 90 Degrees-Rotating Dual-Head Small Animal PET System." Physics in Medicine and Biology 60, no. 15 (2015): 5873-90.

[15] Jingjing Liu, Chien-Min Kao, Shuguo Gu, Peng Xiao, Qingguo Xie. "A PET System Design by Using Mixed Detectors: Resolution Properties." Physics in Medicine and Biology 59, no. 13 (2014): 3517-32.

[16] Daoming Xi, Chien-Min Kao, Wei Liu, Chen Zeng, Xiang Liu and Qingguo Xie, FPGA-only MVT digitizer for TOF PET, IEEE Transactions on Nuclear Science, vol. 60, no. 5, pp. 3253-3261, 2013

[17] Qingguo Xie, Yuanbao Chen, Jun Zhu, Jingjing Liu, Xi Wang, Xin Chen, Ming Niu, Zhongyi Wu, Daoming Xi, Luyao Wang, Peng Xiao, Chin-Tu Chen and Chien-Min Kao, Implementation of LYSO/PSPMT block detector with all digital DAQ system, IEEE Transactions on Nuclear Science, vol. 60, no. 3, pp. 1487-1494, 2013

[18] Xi Wang, Qingguo Xie, Yuanbao Chen and Ming Niu, Advantages of digitally sampling scintillation pulses in pileup processing in PET, IEEE Transactions on Nuclear Science, vol. 59, no. 3, pp. 498-506, 2012

[19] Ming Niu, Chien-Min Kao, Jun Zhu, Peng Xiao, Anwen Long, Robert G. Wagner, Gary Drake, Chin-Tu Chen and Qingguo Xie, Evaluation of multi-pixel photon counters in energy determination for PET imaging, Journal of Instrumentation, vol. 7, no. 4, pp. T04001, 2012

[20] Jing Zhong, Wenzhong Liu, Zhongzhou Du, Paulo Cesar de Morais, Qing Xiang and Qingguo Xie, A noninvasive, remote and precise methodfor temperature and concentration estimation using magnetic nanoparticles, Nanotechnology, vol. 23, no. 3, pp. 075703, 2012.

[21] Ning Guo, Lixin Lang, Haokao Gao, Gang Niu, Dale O. Kiesewetter,Qingguo Xie and Xiaoyuan Chen, Quantitative analysis and parametric imaging of 18F-Labeled monomeric and dimeric RGD peptides using compartment model, Molecular Imaging and Biology, vol. 14, no. 6, pp. 743-752, 2012.

[22] Ning Guo, Linxin Lang, Weihua Li, Dale O. Kiesewetter, Haokao Gao, Gang Niu, Qingguo Xie and Xiaoyuan Chen, Quantitative analysis andcomparison study of [18F] AlF-NOTA-PRGD2, [18F] FPPRGD2 and [68Ga] Ga-NOTA-PRGD2 using a reference tissue model, PLoS One, vol. 7, no. 5, pp. e37506, 2012

[23] Daoming Xi, Qingguo Xie, Jun Zhu, Li Lin, Ming Niu, Peng Xiao, Chin-Tu Chen and Chein-Min Kao, Optimization of the SiPM pixel size for a monolithic PET detector, Physics Procedia, vol. 37, pp. 1497-1503, 2012

[24] Jingjing Liu and Qingguo Xie, "An investigation of local high spatial resolution adaptive PET system," Engineering Sciences. vol. 13, no. 10, pp 105-112, 2011

[25] Jinxia Guo, Xiaoqing Cao, and Qingguo Xie, "Preliminary investigation of relation between PET geometric and system response matrix," Nuclear Electronics and Detection Technology, vol. 31, no. 1, pp. 62-66, 2011

[26] Zhenzhou Deng, Zhiwen Duan, Jingjing Liu, and Qingguo Xie, "Incomplete data CT image reconstruction based on a new scanning mode," Nuclear Electronics and Detection Technology, vol. 31, no. 1, pp. 62-66, 2011

[27] Qingguo Xie, Chien-Min Kao, Xi Wang, Ning Guo, Caigang Zhu, Henry Frisch, William W. Moses, and Chin-Tu Chen, “Potentials of digitally sampling scintillation pulses in timing determination in PET,” IEEE Transactions on Nuclear Science, vol. 56, No. 5, pp. 2607-2613, 2009.

[28] Chien-Min Kao, Qingguo Xie, Yun Dong, Lu Wan, and Chin-Tu Chen, “Development and performance evaluation of a high-sensitivity positron emission tomography scanner dedicated for small-animal imaging,” IEEE Transactions on Nuclear Science, vol. 56, No. 5, pp.2678-2688, 2009.

[29] Heejong Kim , Chien-Min Kao, Qingguo Xie, Henry Frisch, Chin-TuChen, and Fukun Tang, "A multi-threshold method for TOF PET signal processing," Nucl. Inst. and Meth. in Phys. Res. Sect. A, vol. 602, pp. 618-621, 2009

[30] Qingguo Xie, Chien-Min Kao, Zekai Hsiau, and Chin-Tu Chen, “A new approach for pulse processing in Positron Emission Tomography,” IEEE Transactions on Nuclear Science, vol. 52, No. 4, pp988-995, 2005

[31] Zhonghua Deng, Qingguo Xie, “DSP based hardware design of all-digital AC variable speed system,” International Journal Hydroelectric Energy, vol. 23, No. 2, pp55-57, 63, 2005

[32] Qingguo Xie, Shuyun Wan and Jin Zhao, “A systemic design methodology of T-S fuzzy controller”, Electrical Drive, vol. 33, No. 2, pp. 25-27, 62, 2003

[33] Qingguo Xie, Jin Zhao, Shuyun Wan and Yi Shen, “On stability analysis of induction motor”, Control Theory and Application, vol. 19, No. 6, pp. 919-202, 2002

[34] Qingguo Xie, Jin Zhao, Yi Shen and Shuyun Wan, “Speed sensorless control of induction motor using soft-computing methodologies”, Electrical Drive, vol. 32, No. 4, pp. 20- 24, 2002

[35] Qingguo Xie, Yi Shen and Shuyun Wan, “On convergence analysis of Elman neural network”, Computer Engineering and Application, vol.38, No.6, pp65-66, 81, 2002

[36] Qingguo Xie, Song Min, Shuyun Wan and Jin Zhao, “Software design of all digital AC variable speed system”, Computer Engineering and Application, vol.38, No.5, pp207-210, 2002

[37] Qingguo Xie, Shuyun Wan and Jin Zhao, “A systemic design methodology of Elman recurrent network”, Journal of HUST, vol.30, No.3, pp22-24, 2002

[38] Qingguo Xie, Jin Zhao, Shuyun Wan, and Anwen Shen, “An encryption algorithm based on chaotic iteration”, Journal of China Three Gorges University, vol.24, No.2, pp137-138, 2002

[39] Qingguo Xie, Shuyun Wan, Yanchun Yi, Jin Zhao, and Yi Shen, “Speed sensorless control using Elman neural network”, System Engineering and Electronics, vol. 12, No.4, pp. 53-58, 2001

[40] Kee Zeng, Qingguo Xie, Yi Shen, and Shuyun Wan, “Design ideology of component technology-based energy management system”, Electrical Power System Automation, Vol. 25, No. 9, pp.35-37, May 2001

[41] Kee Zeng, Qingguo Xie, Zheng Yang, and Changguo Ke, “Component technology-based electrical power system MIS model”, International Journal Hydroelectric Energy, Vol. 19, No. 1, pp. 75-76, Mar. 2001

[42] Qingguo Xie, Zhonghua Deng, Shuyun Wan, and Jin Zhao, “Modified LIUS algorithm and implementation with DSP”, Computer Engineering and Application, Vol. 37, No. 5, pp.100-101, 125, Feb. 2001

[43] Qingguo Xie, Shuyun Wan, Jin Zhao, and Zhiguo Li, “Phase compensation for direct torque control using fuzzy inference,” International Journal Hydroelectric Energy, Vol. 18, No. 3, pp. 69-72, Sept. 2000

[44] Qingguo Xie, Zhonghua Deng, and Shuyun Wan, “Communication between DSP-based high-speed control system and IBM-PC,” Electrical Drive Automation, Vol. 22, No. 5, pp. 36-38, 58, Sept. 2000

[45] Qingguo Xie, Jin Zhao, Shuyun Wan, and Lijiu Wang, “DSP-based all digital AC drive system,” Electrical Automation, Vol. 22, No. 3, pp. 29-30, May 2000

[46] Kee Zeng, Qingguo Xie, Zhonghua Deng, and Shuyun Wan, “Enhanced RSA algorithms implemented with DSP,” Computer Engineering and Application, Vol. 36, No. 8, pp.68-69, 79, Aug. 2000

[47] Kee Zeng, Qingguo Xie, Yuli Fu, and Shuyun Wan, “An adaptive fuzzy controller for central heating net,” Journal of HUST, Vol. 28, No. 3, Mar. 2000

[48] Qingguo Xie, Hong Gu, Jianhua Yang, and Yinmin Liu “Discussion of Windows as a real-time control platform,” Computer Engineering and Application, Vol. 34, No. 8, 1998

[49] Qingguo Xie, Zhonghua Deng, and Shanmei Cheng, “Application interface design of Intel82530 in high-speed control systems based on TMS32020,” Electrical Drive Automation, Vol. 19, No. 1, 1997

Courses Taught

PET Fundamentals(0705991)

Project

All-Digital PET Imaging Lab in HUST

Multi-modality Animal Imaging Group in WNLO

Hubei Digital PET Engineering Technology Research Center

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